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TPD1 Products

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TG2004H
TopoGEN provides purified Human Tyrosyl DNA Phosphodiesterase (Tdp1) purified to homogeneity to a single 68 kDa band on SDS-PAGE.  Tdp1 is catalytically active and will remove a terminal 3’ phosphotyrosyl group from a specifically designed oligo target site (oligo-Tyr).  Additionally, TopoGEN scientists have demonstrated that Tdp1 will release…
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TopoGEN provides purified Human Tyrosyl DNA Phosphodiesterase (Tdp1) purified to homogeneity to a single 68 kDa band on SDS-PAGE.  Tdp1 is catalytically active and will remove a terminal 3’ phosphotyrosyl group from a specifically designed oligo target site (oligo-Tyr).  Additionally, TopoGEN scientists have demonstrated that Tdp1 will release topo I covalently attached to genomic DNA […]
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TG2016
A rabbit polyclonal antibody was prepared against the native Tdp1 protein.  The purity was greater than 99% as determined by SDS-PAGE.  The antibody is in solution (PBS) at 2.5 unit/ul (see definitions of unit below).  This antibody is ideal for Western blotting applications or immunoflourescent (IF)…
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A rabbit polyclonal antibody was prepared against the native Tdp1 protein.  The purity was greater than 99% as determined by SDS-PAGE.  The antibody is in solution (PBS) at 2.5 unit/ul (see definitions of unit below).  This antibody is ideal for Western blotting applications or immunoflourescent (IF) studies on the cytological localization.  The dilutions of antibody […]
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TG1004
The Tdp1 Assay Kit contains all reagents for routine detection of Tdp1 activity using the tyrosine release assay from the substrate Oligo-Tyr (human tdp1 is sold separately).  The assay is highly specific for Tdp1. Summary: The kit contains reagents and protocols for assaying Tyrosyl DNA Phosphodiesterase (Tdp1).  A procedure…
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The Tdp1 Assay Kit contains all reagents for routine detection of Tdp1 activity using the tyrosine release assay from the substrate Oligo-Tyr (human tdp1 is sold separately).  The assay is highly specific for Tdp1. Summary: The kit contains reagents and protocols for assaying Tyrosyl DNA Phosphodiesterase (Tdp1).  A procedure for making suitable cell extracts is described […]
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