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Topo II

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TG4150
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of…
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TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […]
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$95.00
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TG4130
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of…
Show more (+)
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […]
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$95.00
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TG4120
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of…
Show more (+)
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […]
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$95.00
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TG4170
Ellipticine is a topoisomerase II poison that induces topo II dependent cleavages
$95.00
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TG4140
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of…
Show more (+)
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II.  For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […]
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$95.00
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TG4160
Genistein is an isoflavone and an inhibitor of tyrosine protein kinases.  It has been reported to induce topo II dependent cleavages (Biochem. Pharmacol. 39:737-740 [1990]).  TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II (Note, Genistein may also inhibit topoisomerase I.)  For in vitro cleavage…
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Genistein is an isoflavone and an inhibitor of tyrosine protein kinases.  It has been reported to induce topo II dependent cleavages (Biochem. Pharmacol. 39:737-740 [1990]).  TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II (Note, Genistein may also inhibit topoisomerase I.)  For in vitro cleavage detection, we recom- mend that the drug be […]
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$95.00
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TG4200
HU-331 is a cannabinoid-based quinone with potential anticancer activity.  It has anti-topo IIa activity as a catalytic inhibitor rather than a poison (such as etoposide).    
$85.00
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