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Topo II
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PRODUCT ID | Product Info | Description | Purchase |
|---|---|---|---|
TG4150 |
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of… Show more (+) TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […] Show less (-) |
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TG4130 |
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of… Show more (+) TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […] Show less (-) |
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TG4120 |
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of… Show more (+) TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […] Show less (-) |
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TG4170 |
Ellipticine is a topoisomerase II poison that induces topo II dependent cleavages |
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TG4140 |
TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of… Show more (+) TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II. For in vitro cleavage detection, we recommend that the drug be tested over a wide range of uM concentrations; however, cleavages are strongly influenced by the amount of topoisomerase in the reaction as well as the type of assay being employed (SDSK+ vs. Radioactive […] Show less (-) |
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TG4160 |
Genistein is an isoflavone and an inhibitor of tyrosine protein kinases. It has been reported to induce topo II dependent cleavages (Biochem. Pharmacol. 39:737-740 [1990]). TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II (Note, Genistein may also inhibit topoisomerase I.) For in vitro cleavage… Show more (+) Genistein is an isoflavone and an inhibitor of tyrosine protein kinases. It has been reported to induce topo II dependent cleavages (Biochem. Pharmacol. 39:737-740 [1990]). TopoGEN provides this reagent as a control poison/inhibitor of topoisomerase II (Note, Genistein may also inhibit topoisomerase I.) For in vitro cleavage detection, we recom- mend that the drug be […] Show less (-) |
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TG4200 |
HU-331 is a cannabinoid-based quinone with potential anticancer activity. It has anti-topo IIa activity as a catalytic inhibitor rather than a poison (such as etoposide). |
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