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Product ID | Product Info | Description | Purchase |
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TG1001 |
This kit is designed to allow quick and specific assays for any type II topoisomerase, either eu- or prokaryotic. This kit facilitates the purification and characterization of type II enzymes and contains all reagents necessary for routine assays of Topoisomerase II. |
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TG1015 |
The Human Topoisomerase I Assay Kit from TopoGEN is highly specific for Topo I. It is a simple and straightforward method to measure the loss of supercoiled DNA, or the appearance of relaxed DNA products. |
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TG1030 |
This assay kit contains all the reagents for cytolocalization of Human Top2a using immunofluorescence. The system is optimized for use with FITC or Rhodamine labeled secondary antibody with adherent cells. The method may work with other cells besides human. Mouse, rat and monkey cells will cross react with… Read more (+) This assay kit contains all the reagents for cytolocalization of Human Top2a using immunofluorescence. The system is optimized for use with FITC or Rhodamine labeled secondary antibody with adherent cells. The method may work with other cells besides human. Mouse, rat and monkey cells will cross react with topo II antibody. The antibody is specific […] Show less (-) |
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TG1003 |
The Kit is designed to allow quick and specific detection of DNA gyrase. This kit facilitates the purification and characterization of type II topoisomerase enzymes (DNA Gyrase) and contains all reagents necessary for routine assays of type II enzymes that either have or do not have the ability to supercoil… Read more (+) The Kit is designed to allow quick and specific detection of DNA gyrase. This kit facilitates the purification and characterization of type II topoisomerase enzymes (DNA Gyrase) and contains all reagents necessary for routine assays of type II enzymes that either have or do not have the ability to supercoil. Show less (-) |
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TG1035 |
The immunoprecpitation (IP) kit contains the key reagents and protocol for immunoprecipitating Human Top2a. The method should work well with other cells besides humans. For example, mouse, rat and monkey cells will cross react with topoisomerase II antibody. The antibody is specific for p170 (topo II alpha)… Read more (+) The immunoprecpitation (IP) kit contains the key reagents and protocol for immunoprecipitating Human Top2a. The method should work well with other cells besides humans. For example, mouse, rat and monkey cells will cross react with topoisomerase II antibody. The antibody is specific for p170 (topo II alpha) in human (HeLa) cells and although we presume […] Show less (-) |
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TG1025 |
The purpose of the DNA Intercalator/Unwinding Kit is to determine if a compound induces DNA unwinding characteristic of DNA intercalators. Sufficient materials are provided for at least 50 independent determinations. NOTE: enzyme is not included with this kit. |
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TG1024 |
TopoGEN has extensive experience with assays for topoisomerase inhibition in vivo. This analysis allows the investigator to ascertain whether a novel agent is active against endogenous Top2bin whole cells. An important benefit to this analysis is that one can use any tumor cell or tissue in order to establish clinical… Read more (+) TopoGEN has extensive experience with assays for topoisomerase inhibition in vivo. This analysis allows the investigator to ascertain whether a novel agent is active against endogenous Top2bin whole cells. An important benefit to this analysis is that one can use any tumor cell or tissue in order to establish clinical efficacy against a specific tumor […] Show less (-) |
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TG2000GKIT |
Contains bacterial (E. coli) DNA Gyrase purified to homogeneity based on SDS-Page. |
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TG1040-1 |
TopI-NucEx Kit is designed to allow a researcher to prepare a nuclear extract enriched for topoisomerase I (top1) activity and intact 100 kDa polypeptide. The appropriate assay buffer specific for topo I is included. |
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TG1050-1 |
TopII-NucEx Kit is designed to allow a researcher to prepare a nuclear extract enriched for topoisomerase II (top2) activity. The appropriate assay buffer specific for topo II is included. |
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TG1020 |
High throughput In vivo Complex of Enzyme (ICE) Assay that measures endogenous topoisomerase/genomic DNA covalent complexes. The one day procedure does not require a CsCl centrifugation step. The ICE Assay Kit is topo specific since we provide antibody that corresponds to the topo/DNA complex. |
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TG4060 |
High purity SDS is dissolved in triple glass distilled/deionized, sterile water to 10% (w/v). The ability of each lot to function as an effective topoisomerase denaturant is tested and verified for each lot. |
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TG4038 |
Vial contains 1ml of 10X agarose gel loading buffer ( 0.005% bromophenol blue, 50% glycerol). |
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TG4065 |
20% Sarkosyl |
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TG4035 |
20mM ATP supplied in aqueous buffer (0.5ml). |
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