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Homologous Recombination Reporter Cells
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PRODUCT ID | Product Info | Description | Purchase |
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DR3000 |
DNA Repair pathways in animal cells can be divided into two main categories: HR and NHEJ. HR or homologous recombination is a minor pathway but very important in protecting cells from genotoxicity. The process has two key requirements as well: a homologous sequence, usually available after DNA replication… Show more (+) DNA Repair pathways in animal cells can be divided into two main categories: HR and NHEJ. HR or homologous recombination is a minor pathway but very important in protecting cells from genotoxicity. The process has two key requirements as well: a homologous sequence, usually available after DNA replication when the genome is 4N, and S-phase. […] Show less (-) |
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DR3000-HRHeLa |
This is a cell-based reporter kit designed to allow the customer to screen or identify agents (drugs, natural products, small molecules, synthetics, miRNAs, and genes) that affect or impact the process of HR DNA repair. The kit uses GFP as an in vivo readout for the HR pathway and Crispr-CAS… Show more (+) This is a cell-based reporter kit designed to allow the customer to screen or identify agents (drugs, natural products, small molecules, synthetics, miRNAs, and genes) that affect or impact the process of HR DNA repair. The kit uses GFP as an in vivo readout for the HR pathway and Crispr-CAS gRNA plasmid that drives a […] Show less (-) |
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DR3000-HRHeLa-Sce |
This is a HeLa cell-based reporter kit designed to allow the customer to screen or identify agents (drugs, natural products, small molecules, synthetics, miRNAs, and genes) that affect or impact the process of HR DNA repair. The kit uses GFP as an in situ readout for the HR pathway. |
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DR3000-HRSH-Sce |
DNA Repair pathways in animal cells can be divided into two main categories: HR and NHEJ. HR or homologous recombination is a minor pathway but very important in protecting cells from genotoxicity. HR needs a homologous sequence and is limited to S-phase. A specific reporter based assay for HR… Show more (+) DNA Repair pathways in animal cells can be divided into two main categories: HR and NHEJ. HR or homologous recombination is a minor pathway but very important in protecting cells from genotoxicity. HR needs a homologous sequence and is limited to S-phase. A specific reporter based assay for HR can be very beneficial for drug […] Show less (-) |
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DR3000-HR3T3-Sce |
This is a cell-based reporter kit designed to allow the customer to screen or identify agents (drugs, natural products, small molecules, synthetics, miRNAs, and genes) that affect or impact the process of HR DNA repair. The kit uses GFP as an in vivo readout for the HR pathway and a… Show more (+) This is a cell-based reporter kit designed to allow the customer to screen or identify agents (drugs, natural products, small molecules, synthetics, miRNAs, and genes) that affect or impact the process of HR DNA repair. The kit uses GFP as an in vivo readout for the HR pathway and a plasmid expression vector containing the […] Show less (-) |
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DR3000-HRCN1.4-Sce |
This is the first HR reporter that has been engineered into a neuronally derived mouse cell line model. The CN1.4 cell line is a clone derived from mouse embryonic day 13 neuronal cultures. The line was transformed using the temperature-sensitive SV-40 Large T-antigen. The cell line expresses… Show more (+) This is the first HR reporter that has been engineered into a neuronally derived mouse cell line model. The CN1.4 cell line is a clone derived from mouse embryonic day 13 neuronal cultures. The line was transformed using the temperature-sensitive SV-40 Large T-antigen. The cell line expresses numerous neuronal markers, including neurofilaments, glutamic acid decarboxylase […] Show less (-) |
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