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Topo Enzymes & DNA Gyrases

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TG2000G
Highly purified E. coli DNA Gyrase is offered as a holoenzyme (contains both A,B subunits). This is an excellent reagent for supercoiling plasmids in vitro or for novel drug screens.
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TG2000EC
For use in all Top4 kits available from TopoGEN.
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TG2005HRC
Recombinant Human Topo I Enzyme for use in all Topoisomerase I Kits from TopoGEN.
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TG2000H
We purify Human Topoisomerase IIα (Top2a) using a proprietary method developed by the staff at TopoGEN.  The purified enzyme is completely free of contamination and nucleases.  It alters linking number of a unique topoisomer in steps of two and the major polypeptide detected on SDS-PAGE is 170 kDa…
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We purify Human Topoisomerase IIα (Top2a) using a proprietary method developed by the staff at TopoGEN.  The purified enzyme is completely free of contamination and nucleases.  It alters linking number of a unique topoisomer in steps of two and the major polypeptide detected on SDS-PAGE is 170 kDa.      
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TG2005H-Y723F
TopoGEN now offers a catalytically inactive form of mutant human topoisomerase I purified to homogeneity (single band on SDS-PAGE).  The mutation is a single residue change at the active site tyrosine (which has been changed to phenylalanine).  This preparation is overexpressed in baculovirus and affinity purified as a…
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TopoGEN now offers a catalytically inactive form of mutant human topoisomerase I purified to homogeneity (single band on SDS-PAGE).  The mutation is a single residue change at the active site tyrosine (which has been changed to phenylalanine).  This preparation is overexpressed in baculovirus and affinity purified as a single band on SDS-PAGE of 100 kDa.  […]
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$435.00
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TG2000GSA
Highly purified S. aureus DNA gyrase is a type II topoisomerase encoded by two genes GyrA and GyrB from staphylococcus aureus.  DNA gyrase is an essential topoisomerase that supercoils DNA through a process of strand breakage/resealing and DNA wrapping.  As a type II enzyme, gyrase is unique in…
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Highly purified S. aureus DNA gyrase is a type II topoisomerase encoded by two genes GyrA and GyrB from staphylococcus aureus.  DNA gyrase is an essential topoisomerase that supercoils DNA through a process of strand breakage/resealing and DNA wrapping.  As a type II enzyme, gyrase is unique in its ability to negatively supercoil a relaxed […]
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When you become our customer, we become your partner in research. We review your data and offer valuable input. Feel free to contact us for further information about how we can assist your topoisomerase research endeavors.