SCREENS FOR NOVEL ANTIBIOTICS

SCREENS FOR NOVEL ANTIBIOTICS

Screening for new antibiotics that target DNA Gyrase & Topoisomerase IV. TopoGEN offers powerful and tractable services to identify Gyrase and Topoisomerase IV targeting antibiotics. These drugs can be subdivided into two large groups: 1. Catalytic Inhibitory...
SCREENS FOR NOVEL ANTIBIOTICS

TOPO/DNA COMPLEXES

Topo/DNA Complexes for Genomic Sequencing Studies Genomic Topoisomerase Studies: TopoGEN offers powerful and tractable services to assist you. Topoisomerases are unique DNA binding proteins. They engage the helix in a series of transient breaking-resealing reactions...
BIO-CORRELATIONS

BIO-CORRELATIONS

Bio-Correlations in Clinical Trials Bio-Correlations in Clinical Trials: TopoGEN offers powerful and tractable services to assist: New topo targeting compounds are constantly coming and going. Clinical trials in disease specific applications are active globally....
SCREENS FOR NOVEL ANTIBIOTICS

QUANTIFY YOUR EXTRACTS

topoisomerase activity levels using customer extracts TopoGEN can quantify total topoisomerase I, II activity levels in your specific model cell line. We can provide precise directions on making nuclear extracts and we will quantify topo levels using biochemical...

ANTI-INFECTIVE SCREENS

​E. coli DNA Gyrase, Topo IV, S. aureus DNA Gyrase, Topo IV TopoGEN offers powerful and tractable services to identify Gyrase and Topoisomerase IV targeting antibiotics. These anti-infective drugs can be subdivided into two large groups: 1. Catalytic Inhibitory...