Could Boosting DNA Repair Protect Patients from Chemotherapy Side Effects?
A remarkable new study from investigators at the National Institutes of Health has uncovered an unexpected mechanism underlying one of chemotherapy’s most debilitating side effects: cisplatin-induced peripheral neuropathy. Rather than DNA repair simply protecting neurons, the researchers found that DNA repair itself can become toxic when neurons lack sufficient deoxynucleotide (dNTP) pools to complete the repair process. Their […]