They Said This Breast Cancer Was Untouchable. Now It’s 70% Gone!

This is why TopoGEN is a key player, providing tools that allow anti-cancer drug discovery and facilitate such important findings.
Scientists have designed a new “smart bomb” drug, DM1, that obliterates the deadliest form of breast cancer—triple-negative breast cancer—by hitting two critical targets at once. DM1 latches onto DNA and an overactive cancer protein (TOP2A), shattering tumor cells’ genetic code while sparing healthy tissue. In lab and animal tests, DM1 stopped tumor growth by over 70%, more than doubling the effect of a standard chemo drug (also a topo drug), with fewer side effects. This breakthrough could pave the way for powerful, low-toxicity treatments against cancers that defy today’s therapies.
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