Topo enzymes are sensitive to DNA quality (for example, heavy metal contamination) and not all DNA preps will support activity. All of our DNA products are screened to support topoisomerase (and gyrase) activity. When you do screening assays for DNA cleavages, you must have DNA with minimal contamination of nicked forms. Fortunately, TopoGEN controls plasmid and kDNA stocks for nicked contaminants, so you don’t have to worry about wasting expensive enzymes on inferior DNA substrate.

Name

Kinetoplast DNA (catenated) 25ug

SKU/Part Number

2013-1

Price

$199.00

Brief Description

An Ideal Topo II Substrate

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Name

Kinetoplast DNA (catenated) 50ug

SKU/Part Number

2013-2

Price

$299.00

Brief Description

An Ideal Topo II Substrate

Quantity:

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Name

Kinetoplast DNA (catenated) 250ug

SKU/Part Number

2013-3

Price

$699.00

Brief Description

An Ideal Topo II Substrate

Quantity:

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Name

Linear Kinetoplast DNA Marker 10ug

SKU/Part Number

2017-1

Price

$169.00

Brief Description

An Ideal Topo II Substrate

Quantity:

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Name

Decatenated Kinetoplast DNA Marker 10ug

SKU/Part Number

2020-1

Price

$189.00

Brief Description

An Ideal Topo II Substrate

Quantity:

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Name

pRYG DNA (Topo II Target) 20ug

SKU/Part Number

2023-2

Price

$189.00

Brief Description

A Plasmid Containing Multiple "Clusters" of Topo II Cleavage Sites

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Name

Relaxed pRYG DNA Marker 10ug

SKU/Part Number

2025-1

Price

$109.00

Brief Description

A Plasmid Containing Multiple "Clusters" of Topo II Cleavage Sites

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Name

Linear pRYG DNA Marker 10ug

SKU/Part Number

2028-1

Price

$109.00

Brief Description

A Plasmid Containing Multiple "Clusters" of Topo II Cleavage Sites

Quantity:

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Name

pHOT-1 DNA (Topo I Target) 20ug

SKU/Part Number

2030-2

Price

$199.00

Brief Description

A High Affinity Topo I Cleavage Substrate

Quantity:

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Name

Relaxed pHOT-1 DNA Marker 10ug

SKU/Part Number

2035-1

Price

$129.00

Brief Description

A High Affinity Topo I Cleavage Substrate

Quantity:

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Name

Supercoiled pBR322 (modified) 50ug

SKU/Part Number

2036-1

Price

$229.00

Brief Description

Ideal Plasmid for Assaying any topoisomerase.

Quantity:

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Name

Supercoiled pBR322 (modified) 250ug

SKU/Part Number

2036-2

Price

$559.00

Brief Description

Ideal Plasmid for Assaying any topoisomerase.

Quantity:

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Name

Relaxed pBR322 (modified) 50ug

SKU/Part Number

2037-1

Price

$249.00

Brief Description

Ideal Plasmid for Assaying Supercoiling by DNA gyrase

Quantity:

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Name

Relaxed pBR322 (modified) 250ug

SKU/Part Number

2037-2

Price

$579.00

Brief Description

Ideal Plasmid for Assaying Supercoiling by DNA gyrase

Quantity:

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Related Items

Topo II Assay Kit
Topo II Enzyme
 

Documentation

kDNA Data Sheet
Decat. Assay

Related Items

Topo II Drug Kit
SDS-K+ Precip.
Topo II Enzyme
 

Documentation

pRYG Data Sheet

Related Items

Topo I Drug Kit
Topo I Assay Kit
SDS-K+ Precip.
DNA Unwinding Kit
Topo I Enzyme
 

Documentation

pHOT-1 Data Sheet

Related Items

Gyrase/DNA Assay
Gyrase Enzyme
 

Documentation

pBR322 DNA Data

[Kits] [Enzymes] [DNAs] [Antibodies] [Inhibitors] [Replenishments] [Topo Protocols Reference]
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Substrates taylor-suited for your topo studies.

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